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Anti-FADD Antibody (5V608)

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Catalog No. TMAB-05801

Anti-FADD Antibody (5V608) is a Rabbit antibody targeting FADD. Anti-FADD Antibody (5V608) can be used in WB,IHC-P,IHC-Fr,FCM,IF.

Anti-FADD Antibody (5V608)

Anti-FADD Antibody (5V608)

😃Good
Catalog No. TMAB-05801
Anti-FADD Antibody (5V608) is a Rabbit antibody targeting FADD. Anti-FADD Antibody (5V608) can be used in WB,IHC-P,IHC-Fr,FCM,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FADD Antibody (5V608) is a Rabbit antibody targeting FADD. Anti-FADD Antibody (5V608) can be used in WB,IHC-P,IHC-Fr,FCM,IF.
Ig Type
IgG
Clone
5V608
Reactivity
Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; FCM: 1:50-100; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityExpressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundApoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Antigen Details
Immunogen
A synthesized peptide: mouse Fadd
Antigen Species
Mouse
Gene Name
FADD
Gene ID
Protein Name
FAS-associated death domain protein
Uniprot ID
Function
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Chemical Properties
Molecular WeightTheoretical: 23 kDa. Actual: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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