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Anti-FADD Antibody (5V608) is a Rabbit antibody targeting FADD. Anti-FADD Antibody (5V608) can be used in WB,IHC-P,IHC-Fr,FCM,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-FADD Antibody (5V608) is a Rabbit antibody targeting FADD. Anti-FADD Antibody (5V608) can be used in WB,IHC-P,IHC-Fr,FCM,IF. |
| Ig Type | IgG |
| Clone | 5V608 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; FCM: 1:50-100; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
| Immunogen | A synthesized peptide: mouse Fadd |
| Antigen Species | Mouse |
| Gene Name | FADD |
| Gene ID | |
| Protein Name | FAS-associated death domain protein |
| Uniprot ID | |
| Function | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
| Molecular Weight | Theoretical: 23 kDa. Actual: 28 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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