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Anti-PRNP Antibody (1U499)

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Catalog No. TMAB-11759

Anti-PRNP Antibody (1U499) is a Rabbit antibody targeting PRNP. Anti-PRNP Antibody (1U499) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF,FCM.

Anti-PRNP Antibody (1U499)

Anti-PRNP Antibody (1U499)

😃Good
Catalog No. TMAB-11759
Anti-PRNP Antibody (1U499) is a Rabbit antibody targeting PRNP. Anti-PRNP Antibody (1U499) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PRNP Antibody (1U499) is a Rabbit antibody targeting PRNP. Anti-PRNP Antibody (1U499) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF,FCM.
Ig Type
IgG
Clone
1U499
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Golgi apparatus and Cytoplasm. Nucleus. Accumulates outside the secretory route in the cytoplasm, from where it relocates to the nucleus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Antigen Details
Immunogen
KLH conjugated synthetic peptide: PRNP
Gene Name
PRNP
Gene ID
Protein Name
Major prion protein
Function
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Chemical Properties
Molecular WeightTheoretical: 25 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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