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Anti-PON1 Antibody (4D291)

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Catalog No. TMAB-11634

Anti-PON1 Antibody (4D291) is a Rabbit antibody targeting PON1. Anti-PON1 Antibody (4D291) can be used in WB,IHC-P,IHC-Fr,IP,IF.

Anti-PON1 Antibody (4D291)

Anti-PON1 Antibody (4D291)

Copy Product Info
😃Good
Catalog No. TMAB-11634
Anti-PON1 Antibody (4D291) is a Rabbit antibody targeting PON1. Anti-PON1 Antibody (4D291) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PON1 Antibody (4D291) is a Rabbit antibody targeting PON1. Anti-PON1 Antibody (4D291) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
Clone
4D291
Reactivity
Human
Verified Activity
1. 25 μg total protein per lane of various lysates (see on figure) probed with PON1 monoclonal antibody, unconjugated (TMAB-11634) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PON1 Monoclonal Antibody, Unconjugated (TMAB-11634) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IP: 1:20-50; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space.
Tissue SpecificityPlasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundHydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters.
Antigen Details
Immunogen
A synthesized peptide: human PON1
Antigen Species
Human
Gene Name
PON1
Gene ID
Protein Name
Serum paraoxonase/arylesterase 1
Uniprot ID
Function
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Chemical Properties
Molecular WeightTheoretical: 40 kDa. Actual: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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