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Synonyms: GHR/BP, GHR, GHBP, GH receptor
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-GHR Antibody (5J645) is an antibody targeting GHR. Anti-GHR Antibody (5J645) can be used in ELISA,IF,IHC. |
| Synonyms | GHR/BP, GHR, GHBP, GH receptor |
| Ig Type | Rabbit IgG |
| Clone | 5J645 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200; IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform 1 expression in placenta is predominant in chorion and decidua. Isoform 4 is hig |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Growth hormone receptor |
| Antigen Species | Human |
| Gene Name | GHR |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cell biology, Developmental biology, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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