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Anti-ARTS1 Antibody (2L658)

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Catalog No. TMAB-02852

Anti-ARTS1 Antibody (2L658) is a Rabbit antibody targeting ARTS1. Anti-ARTS1 Antibody (2L658) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-ARTS1 Antibody (2L658)

Anti-ARTS1 Antibody (2L658)

😃Good
Catalog No. TMAB-02852
Anti-ARTS1 Antibody (2L658) is a Rabbit antibody targeting ARTS1. Anti-ARTS1 Antibody (2L658) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ARTS1 Antibody (2L658) is a Rabbit antibody targeting ARTS1. Anti-ARTS1 Antibody (2L658) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
2L658
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass type II membrane protein (Probable).
Tissue SpecificityUbiquitous.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.
Antigen Details
Immunogen
A synthesized peptide: human ERAP1
Antigen Species
Human
Gene Name
ERAP1
Gene ID
Protein Name
Endoplasmic reticulum aminopeptidase 1
Uniprot ID
Function
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
Chemical Properties
Molecular WeightTheoretical: 107 kDa. Actual: 100 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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