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Anti-STIM1 Antibody (8E689) (Synonyms: TAM1, TAM, stromal interaction molecule 1, STRMK, IMD10, GOK, D11S4...)

Catalog No. TMAC-03908 Copy Product Info
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Anti-STIM1 Antibody (8E689) is a Rabbit antibody targeting STIM1. Anti-STIM1 Antibody (8E689) can be used in IHC,IP,WB.

Anti-STIM1 Antibody (8E689)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03908
Synonyms TAM1, TAM, stromal interaction molecule 1, STRMK, IMD10, GOK, D11S4896E

Anti-STIM1 Antibody (8E689) is a Rabbit antibody targeting STIM1. Anti-STIM1 Antibody (8E689) can be used in IHC,IP,WB.

Anti-STIM1 Antibody
(8E689)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-STIM1 Antibody (8E689) is a Rabbit antibody targeting STIM1. Anti-STIM1 Antibody (8E689) can be used in IHC,IP,WB.
SynonymsTAM1, TAM, stromal interaction molecule 1, STRMK, IMD10, GOK, D11S4896E
Ig Type
IgG
Clone
8E689
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of STIM1 on different lysates using anti-STIM1 antibody at 1/1,000 dilution. Positive control: Lane 1: K562, Lane 2: HepG2.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-STIM1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-STIM1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCa2+ influx is essential for a variety of cellular functions including, secretion and transcription. Stromal interaction molecule 1 (Stim1) is a ubiquitously expressed cell surface transmembrane glycoprotein that plays a role in medi-ating Ca2+ influx following the depletion of intracellular Ca2+ stores. Stim1 functions in the endoplasmic reticulum (ER) where it acts as a Ca2+ sensor via its EF-hand domain which causes large conformational changes. When Ca2+ levels drop, Stim1 translocates from the ER to the plasma membrane, where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A/Orai1. Stim2 is a potent inhibitor of Stim1-mediated store-operated calcium (SOC) entry. Stim1 is implicated in tumor growth suppression and stromal-hematopoietic cell interactions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 100 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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