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Anti-Claudin-6/9 Antibody (2D938) (Synonyms: claudin 9, claudin 6)

Catalog No. TMAH-00282 Copy Product Info
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Anti-Claudin-6/9/9 Antibody (2D938) is an antibody targeting Claudin-6/9. Anti-Claudin-6/9/9 Antibody (2D938) can be used in ELISA,FCM.

Anti-Claudin-6/9 Antibody (2D938)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00282
Synonyms claudin 9, claudin 6

Anti-Claudin-6/9/9 Antibody (2D938) is an antibody targeting Claudin-6/9. Anti-Claudin-6/9/9 Antibody (2D938) can be used in ELISA,FCM.

Anti-Claudin-6/9 Antibody
(2D938)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Claudin-6/9/9 Antibody (2D938) is an antibody targeting Claudin-6/9. Anti-Claudin-6/9/9 Antibody (2D938) can be used in ELISA,FCM.
Synonymsclaudin 9, claudin 6
Ig Type
Human IgG1
Clone
2D938
Reactivity
Human
Verified Activity
1. The Binding Activity of Huamn CLDN6 with Anti-CLDN6/9 recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 10 μg/mL can bind Anti-CLDN6/9 recombinant antibody, the EC50 is 1.501-2.035 ng/mL.
2. The Binding Activity of Human CLDN9 with Anti-CLDN6/9 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN9 at 10 μg/mL can bind Anti-CLDN6/9 recombinant antibody, the EC50 is 24.93-35.47 ng/mL.
3. Untransfected HEK293T cells surface (green line) and transfected Human CLDN6 HEK293T stable cells surface (red line) were stained with anti-CLDN6/9 recombinant antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
4. Untransfected MC38 cells (green line) and transfected Human CLDN9 MC38 stable cells (red line) were stained with anti-CLDN6/9 antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
5. Untransfected CHO-K1*10^6 cells, washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
7. The Binding Activity of Macaca fascicularis CLDN6 with Anti-CLDN6/9 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CLDN6 at 5 μg/mL can bind Anti-CLDN6/9 recombinant antibody. The EC50 is 4.186-6.635 ng/mL.
The VLPs is negative control.
8. The Binding Activity of Human CLDN6 with Anti-CLDN6/9 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 2 μg/mL can bind Anti-CLDN6/9 recombinant antibody. The EC50 is 1.243-2.426 ng/mL.
9. The Binding Activity of Human CLDN9 with Anti-CLDN6/9 Recombinant Antibody
Activity:Measured by its binding ability in a functional ELISA. Immobilized Human CLDN9 at 2 μg/ml on an Nickel Coated plate can bind Anti-CLDN6/9 recombinant antibody. The EC50 is 2.812-3.524 ng/mL.
Application
Antibody Type
Monoclonal
Subcellular LocalizationCell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundPlays a major role in tight junction-specific obliteration of the intercellular space. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CLDN6/9 Protein
Antigen Species
Human
Gene Name
CLDN6/9
Gene ID
Uniprot ID
Biology Area
Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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