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Anti-SMYD2 Antibody (2V843)

Catalog No. TMAB-12990 Copy Product Info
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Anti-SMYD2 Antibody (2V843) is a Mouse antibody targeting SMYD2. Anti-SMYD2 Antibody (2V843) can be used in WB,ICC/IF.

Anti-SMYD2 Antibody (2V843)

Copy Product Info
🥰Excellent
Catalog No. TMAB-12990

Anti-SMYD2 Antibody (2V843) is a Mouse antibody targeting SMYD2. Anti-SMYD2 Antibody (2V843) can be used in WB,ICC/IF.

Anti-SMYD2 Antibody
(2V843)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SMYD2 Antibody (2V843) is a Mouse antibody targeting SMYD2. Anti-SMYD2 Antibody (2V843) can be used in WB,ICC/IF.
Ig Type
IgG1, Kappa
Clone
2V843
Reactivity
Human (predicted:Rat)
Verified Activity
Cell line: HepG2
Fixative: 100% Ice-cold methanol
Permeabilization: 0.1% Triton X-100
Primary Ab dilution: 1:50
Primary incubation condition: 4°C overnight
Secondary Ab: Goat Anti-Rabbit IgG
Nuclear counter stain: DAPI (Blue)
Comment: Color green is the positive signal for TMAB-12990
Application
WB
ICC/IF
Recommended Dose
WB: 1:500-1000; ICC/IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasm; cytosol. Nucleus.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]
Antigen Details
Gene Name
SMYD2
Gene ID
56950
Protein Name
N-lysine methyltransferase SMYD2
Function
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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