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Anti-SAE1 Antibody (4G581)
(Synonyms: UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1) Copy Product Info
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Synonyms: UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1
Catalog No. TMAC-03680 Copy Product Info
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Anti-SAE1 Antibody (4G581) is a Rabbit antibody targeting SAE1. Anti-SAE1 Antibody (4G581) can be used in FCM,WB.
Anti-SAE1 Antibody
(4G581)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $297 | 7-10 days | 7-10 days | |
| 100 µL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SAE1 Antibody (4G581) is a Rabbit antibody targeting SAE1. Anti-SAE1 Antibody (4G581) can be used in FCM,WB. |
| Synonyms | UBLE1A, SUMO1 activating enzyme subunit 1, SUA1, HSPC140, AOS1 |
| Ig Type | IgG |
| Clone | 4G581 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of SAE1 on different cell lysates using anti-SAE1 antibody at 1/1,000 dilution. Positive control: Lane 1: SiHa, Lane 2: K562, Lane 3: 293. 2. Flow cytometric analysis of A549 cells with SAE1 antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple).Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.  , |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteasome. AOS-1, also designated SUMO-1-activating enzyme or ubiquitin-like 1-activating enzyme E1A, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. AOS-1 can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human SAE1 aa 150-300 |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Theoretical: 38 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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