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Anti-SHB Antibody (3U496)

Catalog No. TMAB-12760 Copy Product Info
🥰Excellent
Anti-SHB Antibody (3U496) is a Rabbit antibody targeting SHB. Anti-SHB Antibody (3U496) can be used in WB.

Anti-SHB Antibody (3U496)

Copy Product Info
🥰Excellent
Catalog No. TMAB-12760

Anti-SHB Antibody (3U496) is a Rabbit antibody targeting SHB. Anti-SHB Antibody (3U496) can be used in WB.

Anti-SHB Antibody
(3U496)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SHB Antibody (3U496) is a Rabbit antibody targeting SHB. Anti-SHB Antibody (3U496) can be used in WB.
Ig Type
IgG
Clone
3U496
Reactivity
Human,Mouse (predicted:Rat)
Verified Activity
25 ug total protein per lane of various lysates (see on figure) probed with SHB monoclonal antibody, unconjugated (TMAB-12760) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cell membrane. Associates with membrane lipid rafts upon TCR stimulation.
Tissue SpecificityWidely expressed.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAdapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Antigen Details
Immunogen
A synthesized peptide: human SHB
Antigen Species
Human
Gene Name
SHB
Gene ID
Protein Name
SH2 domain-containing adapter protein B
Uniprot ID
Function
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Chemical Properties
Molecular WeightTheoretical: 55 kDa. Actual: 55 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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