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Anti-Cytochrome P450 17A1 Antibody (3S328)
Catalog No. TMAB-04924 Copy Product Info
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Anti-Cytochrome P450 17A1 Antibody (3S328) is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Antibody (3S328) can be used in WB,ICC/IF,FCM.
Anti-Cytochrome P450 17A1 Antibody (3S328)
Copy Product Info🥰Excellent
Catalog No. TMAB-04924
Anti-Cytochrome P450 17A1 Antibody (3S328) is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Antibody (3S328) can be used in WB,ICC/IF,FCM.
Anti-Cytochrome P450 17A1 Antibody
(3S328)
(3S328)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
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| Description | Anti-Cytochrome P450 17A1 Antibody (3S328) is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Antibody (3S328) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 3S328 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Cytochrome P450 17A1 monoclonal antibody, unconjugated (TMAB-04924) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. |
| Immunogen | A synthesized peptide: human Cytochrome P450 17A1 |
| Antigen Species | Human |
| Gene Name | CYP17A1 |
| Gene ID | |
| Protein Name | Steroid 17-alpha-hydroxylase/17, 20 lyase |
| Uniprot ID | |
| Function | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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