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Synonyms: HHLA-2, HHLA2, HHLA 2, HERV-H LTR-associating 2, B7y, B7-H7, B7H7, B7-H5


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $169 | 7-10 days | 7-10 days | |
| 20 µg | $267 | 7-10 days | 7-10 days | |
| 50 µg | $488 | 7-10 days | 7-10 days | |
| 100 µg | $776 | 7-10 days | 7-10 days | |
| 200 µg | $1,230 | 7-10 days | 7-10 days | |
| 500 µg | $2,290 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Biotinylated Human B7-H7, His Tag at 1 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Human CD28H, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test). |
| Description | HHLA2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q9UM44-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | Q9UM44-1 |
| Construction | Ile23-Asn344 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | HHLA-2, HHLA2, HHLA 2, HERV-H LTR-associating 2, B7y, B7-H7, B7H7, B7-H5 |
| Research Background | B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Molecular Weight | 39.88 kDa (Predicted); 55-70 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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