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Anti-Desmoglein 2 Antibody (4J535)
😃Good
Catalog No. TMAB-05101
Anti-Desmoglein 2 Antibody (4J535) is a Rabbit antibody targeting Desmoglein 2. Anti-Desmoglein 2 Antibody (4J535) can be used in FCM, ICC/IF, WB.
Anti-Desmoglein 2 Antibody (4J535)
Anti-Desmoglein 2 Antibody (4J535)
😃Good
Catalog No. TMAB-05101
Anti-Desmoglein 2 Antibody (4J535) is a Rabbit antibody targeting Desmoglein 2. Anti-Desmoglein 2 Antibody (4J535) can be used in FCM, ICC/IF, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Desmoglein 2 Antibody (4J535) is a Rabbit antibody targeting Desmoglein 2. Anti-Desmoglein 2 Antibody (4J535) can be used in FCM, ICC/IF, WB. |
| Ig Type | IgG |
| Clone | 4J535 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:50-200; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. |
| Tissue Specificity | All of the tissues tested and carcinomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. |
| Immunogen | Recombinant Protein: protein within C-terminal human Desmoglein 2 |
| Antigen Species | Human |
| Gene Name | DSG2 |
| Gene ID | |
| Protein Name | Desmoglein-2 |
| Uniprot ID | |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Molecular Weight | Theoretical: 150 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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