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Anti-CCNB1 Antibody (5T567) (Synonyms: G2/mitotic-specific cyclin-B1, CCNB1, CCNB)
Catalog No. TMAC-01033 Copy Product Info
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Anti-CCNB1 Antibody (5T567) is a Rabbit antibody targeting CCNB1. Anti-CCNB1 Antibody (5T567) can be used in ICC/IF,IHC,IP,WB.
Anti-CCNB1 Antibody (5T567)
Copy Product Info🥰Excellent
Catalog No. TMAC-01033
Synonyms G2/mitotic-specific cyclin-B1, CCNB1, CCNB
Anti-CCNB1 Antibody (5T567) is a Rabbit antibody targeting CCNB1. Anti-CCNB1 Antibody (5T567) can be used in ICC/IF,IHC,IP,WB.
Anti-CCNB1 Antibody
(5T567)
(5T567)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CCNB1 Antibody (5T567) is a Rabbit antibody targeting CCNB1. Anti-CCNB1 Antibody (5T567) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | G2/mitotic-specific cyclin-B1, CCNB1, CCNB |
| Ig Type | IgG |
| Clone | 5T567 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Cyclin B1 on different lysates using anti-Cyclin B1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Daudi, Lane 3: K562. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cyclin B1 antibody. Counter stained with hematoxylin.   |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc 1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B enzyme; tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M-phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The specificity of this effect is shown by the inability of either cyclin A or cyclin D1 to display any such stimulation of Cdc25A or Cdc25B. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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