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Anti-UFD1L Antibody (1X809)

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Catalog No. TMAB-13976

Anti-UFD1L Antibody (1X809) is a Rabbit antibody targeting UFD1L. Anti-UFD1L Antibody (1X809) can be used in WB,ICC/IF,FCM.

Anti-UFD1L Antibody (1X809)

Anti-UFD1L Antibody (1X809)

😃Good
Catalog No. TMAB-13976
Anti-UFD1L Antibody (1X809) is a Rabbit antibody targeting UFD1L. Anti-UFD1L Antibody (1X809) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-UFD1L Antibody (1X809) is a Rabbit antibody targeting UFD1L. Anti-UFD1L Antibody (1X809) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
1X809
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic and Nuclear
Tissue SpecificityFound in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundEssential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.
Antigen Details
Immunogen
A synthesized peptide: human UFD1
Antigen Species
Human
Gene Name
UFD1
Gene ID
7353
Protein Name
Ubiquitin recognition factor in ER-associated degradation protein 1
Uniprot ID
Q92890
Function
Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Chemical Properties
Molecular WeightTheoretical: 35 kDa. Actual: 35, 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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