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Anti-SMC4 Antibody (3O43)
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Catalog No. TMAB-12966 Copy Product Info
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Anti-SMC4 Antibody (3O43) is a Rabbit antibody targeting SMC4. Anti-SMC4 Antibody (3O43) can be used in WB,ICC/IF,FCM.
Anti-SMC4 Antibody
(3O43)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µL | $150 | 7-10 days | 7-10 days | |
| 50 µL | $263 | 7-10 days | 7-10 days | |
| 100 µL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SMC4 Antibody (3O43) is a Rabbit antibody targeting SMC4. Anti-SMC4 Antibody (3O43) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 3O43 |
| Reactivity | Human,Mouse |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with SMC4 monoclonal antibody, unconjugated (TMAB-12966) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase. |
| Tissue Specificity | Widely expressed. Higher expression in testis, colon, thymus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. |
| Immunogen | A synthesized peptide: human SMC4 |
| Antigen Species | Human |
| Gene Name | SMC4 |
| Gene ID | |
| Protein Name | Structural maintenance of chromosomes protein 4 |
| Uniprot ID | |
| Function | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. |
| Molecular Weight | Theoretical: 147 kDa. Actual: 175 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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