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Synonyms: β 1, α2β1, VLA-2, GPIa-IIa, CD49b, ITGA1&ITGB1, ITGA&ITGB, Integrin alpha A1 β 1, Integrin alpha A1 beta 1, beta 1, alpha A1 β 1, alpha A1 beta 1, alpha A1


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $81 | 7-10 days | 7-10 days | |
| 10 µg | $123 | 7-10 days | 7-10 days | |
| 20 µg | $193 | 7-10 days | 7-10 days | |
| 50 µg | $348 | 7-10 days | 7-10 days | |
| 100 µg | $553 | 7-10 days | 7-10 days | |
| 200 µg | $878 | 7-10 days | 7-10 days | |
| 500 µg | $1,630 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Integrin alpha 2 beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is G8F2Z5(ITGA2)&A0A7N9D0D7(ITGB1). |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | G8F2Z5(ITGA2)&A0A7N9D0D7(ITGB1) |
| Construction | Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail |
| Protein Purity | > 90% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | β 1, α2β1, VLA-2, GPIa-IIa, CD49b, ITGA1&ITGB1, ITGA&ITGB, Integrin alpha A1 β 1, Integrin alpha A1 beta 1, beta 1, alpha A1 β 1, alpha A1 beta 1, alpha A1 |
| Research Background | The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis. |
| Molecular Weight | 126.69 kDa (ITGA2) and 83.16 kDa (ITGB1) (Predicted); 130-170 kDa (ITGA2) and 100-130 kDa (ITGB1) (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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