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Anti-ITK Antibody (8U484)
Catalog No. TMAB-07837 Copy Product Info
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Anti-ITK Antibody (8U484) is a Rabbit antibody targeting ITK. Anti-ITK Antibody (8U484) can be used in IHC-P,IHC-Fr,FCM,IF.
Anti-ITK Antibody (8U484)
Copy Product Info🥰Excellent
Catalog No. TMAB-07837
Anti-ITK Antibody (8U484) is a Rabbit antibody targeting ITK. Anti-ITK Antibody (8U484) can be used in IHC-P,IHC-Fr,FCM,IF.
Anti-ITK Antibody
(8U484)
(8U484)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ITK Antibody (8U484) is a Rabbit antibody targeting ITK. Anti-ITK Antibody (8U484) can be used in IHC-P,IHC-Fr,FCM,IF. |
| Ig Type | IgG |
| Clone | 8U484 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with ITK Monoclonal Antibody, Unconjugated (TMAB-07837) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Lymph; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with ITK Monoclonal Antibody, Unconjugated (TMAB-07837) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; FCM: 1:50-100; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Localizes to cell surface receptors in the plasma membrane after stimulation with respective receptors (TCR, CD28, CD2) in T-cells. |
| Tissue Specificity | T-cell lines and natural killer cell lines. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement. |
| Immunogen | A synthesized peptide: human ITK |
| Antigen Species | Human |
| Gene Name | ITK |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase ITK/TSK |
| Uniprot ID | |
| Function | Plays a role in T-cell proliferation and differentiation. |
| Molecular Weight | Theoretical: 72 kDa. Actual: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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