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Anti-LAMB1 Antibody (6K439) is a Rabbit antibody targeting LAMB1. Anti-LAMB1 Antibody (6K439) can be used in WB,IHC,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-LAMB1 Antibody (6K439) is a Rabbit antibody targeting LAMB1. Anti-LAMB1 Antibody (6K439) can be used in WB,IHC,FCM. |
Synonyms | Laminin-8 subunit beta, Laminin-6 subunit beta, Laminin-2 subunit beta, Laminin-12 subunit beta, Laminin-10 subunit beta, Laminin-1 subunit beta, Laminin subunit beta-1, Laminin B1 chain, LAMB1 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-Laminin beta 1 antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of A431 cells with Laminin beta 1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
Application | |
Recommended Dose | WB: 1:1000; IHC: 1:100-500; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of a, b, and g chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human Laminin b-1 gene maps to chromosome 7q22 and is ubiquitously expressed in tissues that produce basement membranes. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 198 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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