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Anti-NRF1 Antibody (4L389) is a Mouse antibody targeting NRF1. Anti-NRF1 Antibody (4L389) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
| Description | Anti-NRF1 Antibody (4L389) is a Mouse antibody targeting NRF1. Anti-NRF1 Antibody (4L389) can be used in WB,ICC/IF. |
| Ig Type | IgG2b/Kappa |
| Clone | 4L389 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus |
| Tissue Specificity | Ubiquitously expressed with strongest expression in skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014] |
| Immunogen | KLH conjugated synthetic peptide: human NRF1 |
| Antigen Species | Human |
| Gene Name | NRF1 |
| Gene ID | |
| Protein Name | Nuclear respiratory factor 1 |
| Uniprot ID | |
| Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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