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Anti-GCGR Antibody (7J909) is an antibody targeting GCGR. Anti-GCGR Antibody (7J909) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Human |
Ig Type | Human IgG1 |
Clone | 7J909 |
Reactivity | Human |
Verified Activity | 1. The Binding Activity of Human GCGR with Anti-GCGR recombinant antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GCGR at 2 μg/mL can bind Anti-GCGR recombinant antibody, the EC50 is 14.57-32.56 ng/mL. 2. The Binding Activity of Human GCGR with Anti-GCGR recombinant antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GCGR at 2 μg/mL can bind Anti-GCGR recombinant antibody, the EC50 is 104.1-179.5 ng/mL. |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human GCGR Protein |
Antigen Species | Human |
Gene ID | 2642 |
Uniprot ID | |
Biology Area | Cancer, Metabolism, Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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