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Anti-KATNA1 Antibody (8S283)

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Catalog No. TMAB-07908

Anti-KATNA1 Antibody (8S283) is a Rabbit antibody targeting KATNA1. Anti-KATNA1 Antibody (8S283) can be used in WB,ICC/IF.

Anti-KATNA1 Antibody (8S283)

Anti-KATNA1 Antibody (8S283)

😃Good
Catalog No. TMAB-07908
Anti-KATNA1 Antibody (8S283) is a Rabbit antibody targeting KATNA1. Anti-KATNA1 Antibody (8S283) can be used in WB,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KATNA1 Antibody (8S283) is a Rabbit antibody targeting KATNA1. Anti-KATNA1 Antibody (8S283) can be used in WB,ICC/IF.
Ig Type
IgG
Clone
8S283
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCatalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Antigen Details
Immunogen
A synthesized peptide: human p60 Katanin
Antigen Species
Human
Gene Name
KATNA1
Gene ID
Protein Name
Katanin p60 ATPase-containing subunit A1
Uniprot ID
Function
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth (By similarity).
Chemical Properties
Molecular WeightTheoretical: 56 kDa. Actual: 56 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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