Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-UBC Antibody (1V28)
😃Good
Catalog No. TMAH-01232
Alias UBC, Polyubiquitin-C [Cleaved into: Ubiquitin]
Anti-UBC Antibody (1V28) is an antibody targeting UBC. Anti-UBC Antibody (1V28) can be used in ELISA, FCM.
Anti-UBC Antibody (1V28)
Anti-UBC Antibody (1V28)
😃Good
Catalog No. TMAH-01232Alias UBC, Polyubiquitin-C [Cleaved into: Ubiquitin]
Anti-UBC Antibody (1V28) is an antibody targeting UBC. Anti-UBC Antibody (1V28) can be used in ELISA, FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Mouse Monoclonal Application: ELISA, FCM Reactivity: Human |
| Alias | UBC, Polyubiquitin-C [Cleaved into: Ubiquitin] |
| Ig Type | Mouse IgG2a |
| Clone | 1V28 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing MCF7 cells stained with TMAH-01232 (red line) at 1:50. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 022 events was performed. |
| Application | ELISA, FCM |
| Recommended Dose | FCM:1:20-1:500. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Ubiquitin]: Cytoplasm. Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human UBC Protein |
| Antigen Species | Human |
| Gene ID | 7316 |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Neuroscience, Cell biology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-UBC Antibody (1V28) | purchase Anti-UBC Antibody (1V28) | Anti-UBC Antibody (1V28) cost | order Anti-UBC Antibody (1V28)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.