Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-UBC Antibody (1V28) (Synonyms: UBC, Polyubiquitin-C [Cleaved into: Ubiquitin])

Catalog No. TMAH-01232 Copy Product Info
🥰Excellent
Anti-UBC Antibody (1V28) is an antibody targeting UBC. Anti-UBC Antibody (1V28) can be used in ELISA,FCM.

Anti-UBC Antibody (1V28)

Copy Product Info
🥰Excellent
Catalog No. TMAH-01232
Synonyms UBC, Polyubiquitin-C [Cleaved into: Ubiquitin]

Anti-UBC Antibody (1V28) is an antibody targeting UBC. Anti-UBC Antibody (1V28) can be used in ELISA,FCM.

Anti-UBC Antibody
(1V28)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-UBC Antibody (1V28) is an antibody targeting UBC. Anti-UBC Antibody (1V28) can be used in ELISA,FCM.
SynonymsUBC, Polyubiquitin-C [Cleaved into: Ubiquitin]
Ig Type
Mouse IgG2a
Clone
1V28
Reactivity
Human
Verified Activity
Overlay Peak curve showing MCF7 cells stained with TMAH-01232 (red line) at 1:50. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 022 events was performed.
Application
Recommended Dose
FCM:1:20-1:500.
Antibody Type
Monoclonal
Subcellular Localization[Ubiquitin]: Cytoplasm. Nucleus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundExists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human UBC Protein
Antigen Species
Human
Gene Name
UBC
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Neuroscience, Cell biology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator
Related Tags: buy Anti-UBC Antibody (1V28) | purchase Anti-UBC Antibody (1V28) | Anti-UBC Antibody (1V28) cost | order Anti-UBC Antibody (1V28)