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Anti-Ferritin light chain Antibody (6N112)
😃Good
Catalog No. TMAC-01458
Anti-Ferritin light chain Antibody (6N112) is a Rabbit antibody targeting Ferritin light chain. Anti-Ferritin light chain Antibody (6N112) can be used in WB,ICC/IF.
Anti-Ferritin light chain Antibody (6N112)
Anti-Ferritin light chain Antibody (6N112)
😃Good
Catalog No. TMAC-01458
Anti-Ferritin light chain Antibody (6N112) is a Rabbit antibody targeting Ferritin light chain. Anti-Ferritin light chain Antibody (6N112) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Ferritin light chain Antibody (6N112) is a Rabbit antibody targeting Ferritin light chain. Anti-Ferritin light chain Antibody (6N112) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat,zebrafish |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mammalian ferritins consist of 24 subunits made up of two types of polypeptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. The gene encoding human ferritin heavy chain maps to chromosome 11q13 and the human ferritin light chain gene maps to chromosome 19q13.3-q13.4. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 21 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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