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Anti-CBFB Antibody (1I567) (Synonyms: PEBP2B, core-binding factor, β subunit, core-binding factor, beta subuni...)
Catalog No. TMAC-00628 Copy Product Info
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Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in FCM,IHC,WB.
Anti-CBFB Antibody (1I567)
Copy Product Info🥰Excellent
Catalog No. TMAC-00628
Synonyms PEBP2B, core-binding factor, β subunit, core-binding factor, beta subunit
Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in FCM,IHC,WB.
Anti-CBFB Antibody
(1I567)
(1I567)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in FCM,IHC,WB. |
| Synonyms | PEBP2B, core-binding factor, β subunit, core-binding factor, beta subunit |
| Ig Type | IgG |
| Clone | 1I567 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CBFb antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CBFb antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of SiHa cells with CBFb antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.    |
| Application | |
| Recommended Dose | IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The transcription factor Polyomavirus enhancer binding protein 2 (PEBP2), also designated Osf2 (Osteoblast-specific transcription factor), CBFA1 (Core Binding Factor) and AML3 (Acute myeloid leukemia), is composed of two subunits, a and b, which are essential for the regulation of hematopoiesis and osteogenesis. The PEBP2a subunits, PEBP2aA, PEBP2aB and PEBP2aC, are encoded by three RUNX genes, all of which contain a 128-amino acid region homologous to the highly conserved Drosophila segmentation gene, Runt. This region is involved in DNA binding and heterodimerization with the regulatory b subunit, which facilitates DNA binding of the a subunit. Both subunits are required for in vivo function; the disruption of either gene results in a lack of definitive hematopoiesis followed by embryo death in utero due to hemorrhage in the central nervous system. The gene encoding PEBP2b is the target of chromosomal inversion 16 (p13;q22) with the smooth muscle myosin heavy chain, producing a chimeric gene, PEBP2b/CBFB-SMMHC, that is associated with human acute myeloid leukemia. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human CBFb aa 1-200 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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