Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-CBFB Antibody (1I567)
😃Good
Catalog No. TMAC-00628
Alias PEBP2B, core-binding factor, β subunit, core-binding factor, beta subunit
Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in WB,IHC,FCM.
Anti-CBFB Antibody (1I567)
Anti-CBFB Antibody (1I567)
😃Good
Catalog No. TMAC-00628Alias PEBP2B, core-binding factor, β subunit, core-binding factor, beta subunit
Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in WB,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CBFB Antibody (1I567) is a Rabbit antibody targeting CBFB. Anti-CBFB Antibody (1I567) can be used in WB,IHC,FCM. |
| Synonyms | PEBP2B, core-binding factor, β subunit, core-binding factor, beta subunit |
| Ig Type | IgG |
| Clone | 1I567 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CBFb antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CBFb antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of SiHa cells with CBFb antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The transcription factor Polyomavirus enhancer binding protein 2 (PEBP2), also designated Osf2 (Osteoblast-specific transcription factor), CBFA1 (Core Binding Factor) and AML3 (Acute myeloid leukemia), is composed of two subunits, a and b, which are essential for the regulation of hematopoiesis and osteogenesis. The PEBP2a subunits, PEBP2aA, PEBP2aB and PEBP2aC, are encoded by three RUNX genes, all of which contain a 128-amino acid region homologous to the highly conserved Drosophila segmentation gene, Runt. This region is involved in DNA binding and heterodimerization with the regulatory b subunit, which facilitates DNA binding of the a subunit. Both subunits are required for in vivo function; the disruption of either gene results in a lack of definitive hematopoiesis followed by embryo death in utero due to hemorrhage in the central nervous system. The gene encoding PEBP2b is the target of chromosomal inversion 16 (p13;q22) with the smooth muscle myosin heavy chain, producing a chimeric gene, PEBP2b/CBFB-SMMHC, that is associated with human acute myeloid leukemia. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human CBFb aa 1-200 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 22 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Anti-CBFB Antibody (1I567) | purchase Anti-CBFB Antibody (1I567) | Anti-CBFB Antibody (1I567) cost | order Anti-CBFB Antibody (1I567) | Anti-CBFB Antibody (1I567) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.