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Anti-CD144/VE Cadherin Antibody (9I480)

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Catalog No. TMAB-03851

Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP.

Anti-CD144/VE Cadherin Antibody (9I480)

Anti-CD144/VE Cadherin Antibody (9I480)

😃Good
Catalog No. TMAB-03851
Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP.
Ig Type
IgG
Clone
9I480
Reactivity
Mouse
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.
Tissue SpecificityEndothelial tissues and brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThis gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Antigen Details
Immunogen
A synthesized peptide: mouse Cadherin 5
Antigen Species
Mouse
Gene Name
CDH5
Gene ID
Protein Name
Cadherin-5
Uniprot ID
Function
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Chemical Properties
Molecular WeightTheoretical: 88 kDa. Actual: 90, 125 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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