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Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
| Description | Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Clone | 9I480 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| Tissue Specificity | Endothelial tissues and brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. |
| Immunogen | A synthesized peptide: mouse Cadherin 5 |
| Antigen Species | Mouse |
| Gene Name | CDH5 |
| Gene ID | |
| Protein Name | Cadherin-5 |
| Uniprot ID | |
| Function | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. |
| Molecular Weight | Theoretical: 88 kDa. Actual: 90, 125 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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