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Anti-Vitamin D3 receptor Antibody (6S476)

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Catalog No. TMAB-14116

Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP.

Anti-Vitamin D3 receptor Antibody (6S476)

Anti-Vitamin D3 receptor Antibody (6S476)

😃Good
Catalog No. TMAB-14116
Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP.
Ig Type
IgG
Clone
6S476
Reactivity
Human,Mouse (predicted:Rat)
Application
Recommended Dose
WB: 1:500-2000; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundNuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR.
Antigen Details
Immunogen
A synthesized peptide: human Vitamin D3 receptor
Antigen Species
Human
Gene Name
VDR
Gene ID
Protein Name
Vitamin D3 receptor
Uniprot ID
Function
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone ensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Chemical Properties
Molecular WeightTheoretical: 48 kDa. Actual: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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