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Anti-Vitamin D3 receptor Antibody (6S476)
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Catalog No. TMAB-14116
Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP.
Anti-Vitamin D3 receptor Antibody (6S476)
Anti-Vitamin D3 receptor Antibody (6S476)
Copy Product Info😃Good
Catalog No. TMAB-14116
Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Vitamin D3 receptor Antibody (6S476) is a Rabbit antibody targeting Vitamin D3 receptor. Anti-Vitamin D3 receptor Antibody (6S476) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 6S476 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with TMAB-14116 monoclonal antibody, unconjugated (TMAB-14116) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. |
| Immunogen | A synthesized peptide: human Vitamin D3 receptor |
| Antigen Species | Human |
| Gene Name | VDR |
| Gene ID | |
| Protein Name | Vitamin D3 receptor |
| Uniprot ID | |
| Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone ensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. |
| Molecular Weight | Theoretical: 48 kDa. Actual: 48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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