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Anti-Von Willebrand Factor/vWF Antibody (5Q448) (Synonyms: VWF, VWD, F8VWF)
Catalog No. TMAC-04268 Copy Product Info
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Anti-Von Willebrand Factor/vWF Antibody (5Q448) is a Rabbit antibody targeting Von Willebrand Factor/vWF. Anti-Von Willebrand Factor/vWF Antibody (5Q448) can be used in IHC,WB.
Anti-Von Willebrand Factor/vWF Antibody (5Q448)
Copy Product Info🥰Excellent
Catalog No. TMAC-04268
Synonyms VWF, VWD, F8VWF
Anti-Von Willebrand Factor/vWF Antibody (5Q448) is a Rabbit antibody targeting Von Willebrand Factor/vWF. Anti-Von Willebrand Factor/vWF Antibody (5Q448) can be used in IHC,WB.
Anti-Von Willebrand Factor/vWF Antibody
(5Q448)
(5Q448)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Von Willebrand Factor/vWF Antibody (5Q448) is a Rabbit antibody targeting Von Willebrand Factor/vWF. Anti-Von Willebrand Factor/vWF Antibody (5Q448) can be used in IHC,WB. |
| Synonyms | VWF, VWD, F8VWF |
| Ig Type | IgG |
| Clone | 5Q448 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Von Willebrand Factor antibody. Counter stained with hematoxylin. 2. Western blot analysis of VWF expression in human serum lysate.   |
| Application | |
| Recommended Dose | WB: 1:500-2000 IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Von Willebrand disease is a congenital bleeding disorder caused by defects in the von Willebrand factor protein (VWF). VWF is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets, and it is involved in the coagulation of blood at injury sites. VWF acts as a carrier protein for Factor VIII, a cofactor required for coagulation, and it promotes platelet adhesion and aggregation. Several factors are known to stimulate the binding of VWF to platelets, including glycoprotein 1b, ristocetin, botrocetin, collagen, sulphatides and heparin. Of the several domains contained within VWF, the A1, A2 and A3 domains have been shown to mediate this activation. VWF is thought to undergo a variety of posttranslational modifications that influence the affinity and availability for Factor VII, including cleavage of the propeptide and formation of N-terminal intersubunit disulfide bonds. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 309 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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