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Anti-BTLA Antibody (2R520)
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Catalog No. TMAH-00123
Alias CD272, BTLA1
Anti-BTLA Antibody (2R520) is an antibody targeting BTLA. Anti-BTLA Antibody (2R520) can be used in ELISA, FCM.
Anti-BTLA Antibody (2R520)
Anti-BTLA Antibody (2R520)
😃Good
Catalog No. TMAH-00123Alias CD272, BTLA1
Anti-BTLA Antibody (2R520) is an antibody targeting BTLA. Anti-BTLA Antibody (2R520) can be used in ELISA, FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, FCM Reactivity: Human |
| Alias | CD272, BTLA1 |
| Ig Type | Human IgG4 |
| Clone | 2R520 |
| Reactivity | Human |
| Verified Activity | 1. The Binding Activity of Human BTLA with Anti-BTLA Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human BTLA at 2 μg/mL can bind Anti-BTLA recombinant antibody, the EC50 is 11.56-13.00 ng/mL. 2. Untransfected Jurkat cells surface (green line) and transfected Human BTLA Jurkat stable cells surface (red line) were stained with anti-BTLA antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 3. Untransfected CHO-K1*10^6 cells, washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
| Application | ELISA, FCM |
| Recommended Dose | FCM:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human BTLA Protein |
| Antigen Species | Human |
| Gene ID | 151888 |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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