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Anti-BTLA Antibody (2R520) (Synonyms: CD272, BTLA1)
Catalog No. TMAH-00123 Copy Product Info
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Anti-BTLA Antibody (2R520) is an antibody targeting BTLA. Anti-BTLA Antibody (2R520) can be used in ELISA,FCM.
Anti-BTLA Antibody (2R520)
Copy Product Info🥰Excellent
Catalog No. TMAH-00123
Synonyms CD272, BTLA1
Anti-BTLA Antibody (2R520) is an antibody targeting BTLA. Anti-BTLA Antibody (2R520) can be used in ELISA,FCM.
Anti-BTLA Antibody
(2R520)
(2R520)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-BTLA Antibody (2R520) is an antibody targeting BTLA. Anti-BTLA Antibody (2R520) can be used in ELISA,FCM. |
| Synonyms | CD272, BTLA1 |
| Ig Type | Human IgG4 |
| Clone | 2R520 |
| Reactivity | Human |
| Verified Activity | 1. The Binding Activity of Human BTLA with Anti-BTLA Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human BTLA at 2 μg/mL can bind Anti-BTLA recombinant antibody, the EC50 is 11.56-13.00 ng/mL. 2. Untransfected Jurkat cells surface (green line) and transfected Human BTLA Jurkat stable cells surface (red line) were stained with anti-BTLA antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 3. Untransfected CHO-K1*10^6 cells, washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
| Application | |
| Recommended Dose | FCM:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human BTLA Protein |
| Antigen Species | Human |
| Gene Name | BTLA |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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