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Synonyms: LICOS, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP1B7-like protein Gl50, B7RP-1, B7RP1, B7-H2B7-related protein 1, B7-H2, B7H2


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Rat B7-H2, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Mouse ICOS, hFc Tag with the EC50 of 28.2 ng/ml determined by ELISA (QC Test). |
| Description | B7-H2/ICOSLG Protein, Rat, Recombinant (His) is expressed in HEK293 Cells. The accession number is F1LVL2. |
| Species | Rat |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | F1LVL2 |
| Construction | Glu25-Lys261 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC |
| Endotoxin | < 0.1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | LICOS, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP1B7-like protein Gl50, B7RP-1, B7RP1, B7-H2B7-related protein 1, B7-H2, B7H2 |
| Research Background | B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. |
| Molecular Weight | 28.52 kDa (Predicted); 50-70 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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