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Synonyms: solute carrier family 3 (amino acid transporter heavy chain), member 2, NACAE, MDU-1, MDU1, MDU 1, CD98HC, CD-98, CD98, CD 98, 4T2HC, 4F2HC, 4F2


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human CD98, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated CD98 Antibody, hFc Tag with the EC50 of 16.4 ng/ml determined by ELISA (QC Test). |
| Description | CD98 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is AAH01061. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-hFc (IgG1) |
| Accession Number | AAH01061 |
| Construction | Arg206-Ala630 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | solute carrier family 3 (amino acid transporter heavy chain), member 2, NACAE, MDU-1, MDU1, MDU 1, CD98HC, CD-98, CD98, CD 98, 4T2HC, 4F2HC, 4F2 |
| Research Background | The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells. |
| Molecular Weight | 72.38 kDa (Predicted); 80-100 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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