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Anti-Cytokeratin 14 Antibody (1M751)
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Catalog No. TMAB-04938
Anti-Cytokeratin 14 Antibody (1M751) is a Rabbit antibody targeting Cytokeratin 14. Anti-Cytokeratin 14 Antibody (1M751) can be used in IHC-P,IHC-Fr,IF.
Anti-Cytokeratin 14 Antibody (1M751)
Anti-Cytokeratin 14 Antibody (1M751)
😃Good
Catalog No. TMAB-04938
Anti-Cytokeratin 14 Antibody (1M751) is a Rabbit antibody targeting Cytokeratin 14. Anti-Cytokeratin 14 Antibody (1M751) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cytokeratin 14 Antibody (1M751) is a Rabbit antibody targeting Cytokeratin 14. Anti-Cytokeratin 14 Antibody (1M751) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 1M751 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. |
| Tissue Specificity | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq]. |
| Immunogen | Recombinant Protein: human Cytokeratin 14 protein, around C-terminal 150aa |
| Antigen Species | Human |
| Gene Name | KRT14 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 14 |
| Uniprot ID | |
| Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
| Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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