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Anti-TMEM106B Antibody (2Z232)

Catalog No. TMAB-13588 Copy Product Info
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Anti-TMEM106B Antibody (2Z232) is a Mouse antibody targeting TMEM106B. Anti-TMEM106B Antibody (2Z232) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-TMEM106B Antibody (2Z232)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13588

Anti-TMEM106B Antibody (2Z232) is a Mouse antibody targeting TMEM106B. Anti-TMEM106B Antibody (2Z232) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-TMEM106B Antibody
(2Z232)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TMEM106B Antibody (2Z232) is a Mouse antibody targeting TMEM106B. Anti-TMEM106B Antibody (2Z232) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG2a, Kappa
Clone
2Z232
Reactivity
Human
Verified Activity
1. Tissue: Human colon
Section type: Formalin fixed & Paraffin-embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:100
Primary ab incubation condition: 1 hour at room temperature
Counter stain: Hematoxylin
Comment: Color brown is the positive signal for TMAB-13588
2. Tissue: Human cerebellum
Section type: Formalin fixed & Paraffin-embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:100
Primary ab incubation condition: 1 hour at room temperature
Counter stain: Hematoxylin
Comment: Color brown is the positive signal for TMAB-13588
3. Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition: 4°C, overnight
Lysate: HeLa, SH-SY5Y, U87MG
Protein loading quantity: 20 μg
Exposure time: 60 s
Predicted MW: 40 kDa
Observed MW: 40 kDa
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationLate endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein.
Tissue SpecificityExpressed in frontal cortex.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.
Antigen Details
Gene Name
TMEM106B
Gene ID
Protein Name
Transmembrane protein 106B
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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