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Anti-Lunatic Fringe Antibody (9Y9)

😃Good
Catalog No. TMAB-08451

Anti-Lunatic Fringe Antibody (9Y9) is a Rabbit antibody targeting Lunatic Fringe. Anti-Lunatic Fringe Antibody (9Y9) can be used in WB.

Anti-Lunatic Fringe Antibody (9Y9)

Anti-Lunatic Fringe Antibody (9Y9)

😃Good
Catalog No. TMAB-08451
Anti-Lunatic Fringe Antibody (9Y9) is a Rabbit antibody targeting Lunatic Fringe. Anti-Lunatic Fringe Antibody (9Y9) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Lunatic Fringe Antibody (9Y9) is a Rabbit antibody targeting Lunatic Fringe. Anti-Lunatic Fringe Antibody (9Y9) can be used in WB.
Ig Type
IgG
Clone
9Y9
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationGolgi apparatus membrane; Single-pass type II membrane protein
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundGlycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.
Antigen Details
Immunogen
A synthesized peptide: human LFNG
Antigen Species
Human
Gene Name
LFNG
Gene ID
Protein Name
beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe
Uniprot ID
Function
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning.
Chemical Properties
Molecular WeightTheoretical: 42 kDa. Actual: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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