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Anti-Involucrin Antibody (8Q256)
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Catalog No. TMAC-02195
Alias IVL, Involucrin, INVO_HUMAN
Anti-Involucrin Antibody (8Q256) is a Rabbit antibody targeting Involucrin. Anti-Involucrin Antibody (8Q256) can be used in WB,IHC,FCM.
Anti-Involucrin Antibody (8Q256)
Anti-Involucrin Antibody (8Q256)
😃Good
Catalog No. TMAC-02195Alias IVL, Involucrin, INVO_HUMAN
Anti-Involucrin Antibody (8Q256) is a Rabbit antibody targeting Involucrin. Anti-Involucrin Antibody (8Q256) can be used in WB,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Involucrin Antibody (8Q256) is a Rabbit antibody targeting Involucrin. Anti-Involucrin Antibody (8Q256) can be used in WB,IHC,FCM. |
| Synonyms | IVL, Involucrin, INVO_HUMAN |
| Ig Type | IgG |
| Clone | 8Q256 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Western blot analysis of Involucrin on human skin tissue lysate using Involucrin antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Involucrin antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of A431 cells with Involucrin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Involucrin is a precursor protein of the keratinocyte cornified envelope, which is formed beneath the inner surface of the cell membrane during terminal differentiation. During keratinocyte terminal differentiation, glutamine residues of involucrin become covalently cross-linked to other envelope precursors via covalent epsilon-(gamma-glutamyl) lysine bonds. Moreover, its large size allows involucrin to cross-link molecules that are separated by substantial distances in the cornified envelope. These properties allow a single involucrin molecule to form multiple cross-links, in multiple spatial planes, with other envelope precursors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 120 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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