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Anti-Integrin beta 4/CD104 Antibody (9Y971)
Catalog No. TMAB-07752 Copy Product Info
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Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Integrin beta 4/CD104 Antibody (9Y971)
Copy Product Info🥰Excellent
Catalog No. TMAB-07752
Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Integrin beta 4/CD104 Antibody
(9Y971)
(9Y971)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 9Y971 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Mouse Skin; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Integrin beta 4/CD104 Monoclonal Antibody, Unconjugated (TMAB-07752) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Pancreas; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Integrin beta 4/CD104 Monoclonal Antibody, Unconjugated (TMAB-07752) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Integrin beta 4/CD104 Monoclonal Antibody, Unconjugated (TMAB-07752) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Integrin beta 4/CD104 Monoclonal Antibody, Unconjugated (TMAB-07752) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 5. 25 μg total protein per lane of various lysates (see on figure) probed with Integrin beta 4/CD104 monoclonal antibody, unconjugated (TMAB-07752) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes. |
| Tissue Specificity | Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. |
| Immunogen | A synthesized peptide: human Integrin beta 4 |
| Antigen Species | Human |
| Gene Name | ITGB4 |
| Gene ID | |
| Protein Name | Integrin beta-4 |
| Uniprot ID | |
| Function | Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. |
| Molecular Weight | Theoretical: 202 kDa. Actual: 210 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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