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Anti-Integrin beta 4/CD104 Antibody (9Y971)

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Catalog No. TMAB-07752

Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Integrin beta 4/CD104 Antibody (9Y971)

Anti-Integrin beta 4/CD104 Antibody (9Y971)

😃Good
Catalog No. TMAB-07752
Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Integrin beta 4/CD104 Antibody (9Y971) is a Rabbit antibody targeting Integrin beta 4/CD104. Anti-Integrin beta 4/CD104 Antibody (9Y971) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
9Y971
Reactivity
Human,Mouse
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes.
Tissue SpecificityIntegrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIntegrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.
Antigen Details
Immunogen
A synthesized peptide: human Integrin beta 4
Antigen Species
Human
Gene Name
ITGB4
Gene ID
3691
Protein Name
Integrin beta-4
Uniprot ID
P16144
Function
Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.
Chemical Properties
Molecular WeightTheoretical: 202 kDa. Actual: 210 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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