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Anti-STRAP Antibody (5Y959)
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Catalog No. TMAB-13244
Anti-STRAP Antibody (5Y959) is a Mouse antibody targeting STRAP. Anti-STRAP Antibody (5Y959) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Anti-STRAP Antibody (5Y959)
Anti-STRAP Antibody (5Y959)
😃Good
Catalog No. TMAB-13244
Anti-STRAP Antibody (5Y959) is a Mouse antibody targeting STRAP. Anti-STRAP Antibody (5Y959) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-STRAP Antibody (5Y959) is a Mouse antibody targeting STRAP. Anti-STRAP Antibody (5Y959) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG1, Kappa |
| Clone | 5Y959 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Localizedpredominantly in the cytoplasm but also found in the nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Enables RNA binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of transforming growth factor beta receptor signaling pathway; and spliceosomal snRNP assembly. Located in cytosol. Part of SMN complex. Implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human STRAP |
| Antigen Species | Human |
| Gene Name | STRAP |
| Gene ID | |
| Protein Name | Serine-threonine kinase receptor-associated protein |
| Uniprot ID | |
| Function | The SMN complex plays an essential role in spliceosomalsnRNP assembly in the cytoplasm and is required for pre-mRNAsplicing in the nucleus. STRAP may play a role in the cellulardistribution of the SMN complex. Negatively regulates TGF-betasignaling but positively regulates the PDPK1 kinase activity byenhancing its autophosphorylation and by significantly reducing theassociation of PDPK1 with 14-3-3 protein. |
| Molecular Weight | Theoretical: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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