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Anti-ILK Antibody (7G881)

Catalog No. TMAB-07682 Copy Product Info
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Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.

Anti-ILK Antibody (7G881)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07682

Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.

Anti-ILK Antibody
(7G881)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
Clone
7G881
Reactivity
Human,Mouse,Rat
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with ILK monoclonal antibody, unconjugated (TMAB-07682) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue SpecificityHighly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIntegrin-linked kinases (ILKs) couple integrins and growth factors to downstream pathways involved in cell survival, cell cycle control, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extracellular matrix (ECM) and growth factor receptors to the actin cytoskeleton through interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin.
Antigen Details
Immunogen
A synthesized peptide: human ILK
Antigen Species
Human
Gene Name
ILK
Gene ID
Protein Name
Integrin-linked protein kinase
Uniprot ID
Function
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Chemical Properties
Molecular WeightTheoretical: 51 kDa. Actual: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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