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Anti-ILK Antibody (7G881)

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Catalog No. TMAB-07682

Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.

Anti-ILK Antibody (7G881)

Anti-ILK Antibody (7G881)

😃Good
Catalog No. TMAB-07682
Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ILK Antibody (7G881) is a Rabbit antibody targeting ILK. Anti-ILK Antibody (7G881) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
Clone
7G881
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
IP
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue SpecificityHighly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIntegrin-linked kinases (ILKs) couple integrins and growth factors to downstream pathways involved in cell survival, cell cycle control, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extracellular matrix (ECM) and growth factor receptors to the actin cytoskeleton through interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin.
Antigen Details
Immunogen
A synthesized peptide: human ILK
Antigen Species
Human
Gene Name
ILK
Gene ID
3611
Protein Name
Integrin-linked protein kinase
Uniprot ID
Q13418
Function
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Chemical Properties
Molecular WeightTheoretical: 51 kDa. Actual: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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