Immobilized Human CD83, His Tag at 0.5 μg/ml (100 μl/Well) on the plate. Dose response curve for Anti-CD83 Antibody, hFc Tag with the EC50 of 8.6 ng/ml determined by ELISA.

CD83 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q01151-1.

Human

HEK293 Cells

MODY10,IRDN,insulin,INS,ILPR,IDDM2,IDDM1,IDDM

Thr20-Ala143

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear.