HGFR/c-Met Protein, Human, Recombinant (His) V2

Name: HGFR/c-Met Protein, Human, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-01296U
Rating: 4.5 (1 reviews)

(Synonyms: Tyrosine-protein kinase Met, SF receptor, Proto-oncogene c-Met, MET, HGF/SF receptor, HGF receptor, Hepatocyte growth factor receptor) Copy Product Info

Synonyms: Tyrosine-protein kinase Met, SF receptor, Proto-oncogene c-Met, MET, HGF/SF receptor, HGF receptor, Hepatocyte growth factor receptor

Catalog No. TMPY-01296U Copy Product Info

HGFR/c-Met Protein, Human, Recombinant (His) V2 is expressed in HEK293 mammalian cells with His tag. The accession number is P08581-1.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$88	7-10 days	7-10 days
25 µg	$182	-	In Stock
50 µg	$285	7-10 days	7-10 days
100 µg	$480	7-10 days	7-10 days
500 µg	$2,050	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human HGF R, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human HGF, hFc Tag with the EC50 of 10.1 ng/ml determined by ELISA. (QC Test) Immobilized Human HGF R, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HGF R Antibody, hFc Tag with the EC50 of 15.6 ng/ml determined by ELISA.
Description	HGFR/c-Met Protein, Human, Recombinant (His) V2 is expressed in HEK293 mammalian cells with His tag. The accession number is P08581-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P08581-1
Construction	Glu25-Thr932
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Tyrosine-protein kinase Met, SF receptor, Proto-oncogene c-Met, MET, HGF/SF receptor, HGF receptor, Hepatocyte growth factor receptor
Research Background	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.

Chemical Properties

Molecular Weight	32.5 kDa (α chain) and 72.1 kDa (β chain) (Predicted); 45-60 kDa (α subunit) and 80-100 kDa (β subunit) (Reducing conditions due to glycosylation)
Relative Density.	no data available

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.