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Anti-SorLA Antibody (1G832)

Catalog No. TMAB-13048 Copy Product Info
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Anti-SorLA Antibody (1G832) is a Rabbit antibody targeting SorLA. Anti-SorLA Antibody (1G832) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SorLA Antibody (1G832)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13048

Anti-SorLA Antibody (1G832) is a Rabbit antibody targeting SorLA. Anti-SorLA Antibody (1G832) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SorLA Antibody
(1G832)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SorLA Antibody (1G832) is a Rabbit antibody targeting SorLA. Anti-SorLA Antibody (1G832) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1G832
Reactivity
Human,Mouse,Rat
Verified Activity
Western blot analysis of SH-SY5Y cell lysate. Using SorLA (TMAB-13048) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
Tissue SpecificityExpressed mainly in brain, where it is most abundant in the cerebellum, cerebral cortex and the occipital pole; low expression in the putamen and the thalamus. According to PubMed:9157966, found in spinal cord, testis, liver, kidney and pancreas with detectable levels in placenta, lung and heart. According to PubMed:8940146, expressed in the prostate, ovary, thyroid and spleen, but not found in kidney, liver, lung, skeletal muscle, bone marrow and adrenals.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundSorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated.
Antigen Details
Immunogen
A synthesized peptide: human Sortilin related receptor
Antigen Species
Human
Gene Name
SORL1
Gene ID
6653
Protein Name
Sortilin-related receptor
Uniprot ID
Q92673
Function
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.
Chemical Properties
Molecular WeightTheoretical: 248 kDa. Actual: 270 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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