AURORA A, Human, Recombinant (GST)

Name: AURORA A, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPC-00057
Rating: 4.5 (1 reviews)

(Synonyms: Aurora kinase A, Aurora 2, Aurka, ARK-1) Copy Product Info

Synonyms: Aurora kinase A, Aurora 2, Aurka, ARK-1

Catalog No. TMPC-00057 Copy Product Info

AURORA A, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is O14965.

Pack Size	Price	USA Stock	Global Stock	Quantity
10 µg	$1,390	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Representative specific activity data for AURORA A were obtained using different assay formats: - 84 nmol/min/mg, determined by radioactive kinase assay - 43 nmol/min/mg, determined by ADP-Glo kinase assay, corresponding to 77 nmol/min/mg in the radioactive kinase assay Different lots may be tested using different assay methods; therefore, values obtained using different assay formats are not directly comparable.
Description	AURORA A, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is O14965.
Species	Human
Expression System	Baculovirus-Insect Cells
Tag	N-GST
Accession Number	O14965
Construction	Recombinant full length human AURORA A was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.
Protein Purity	>70% as determined by SDS-PAGE.
Formulation	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Synonyms	Aurora kinase A, Aurora 2, Aurka, ARK-1
Research Background	The Aurora kinase A protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 1. Multiple transcript variants encoding the same protein have been found for this gene.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

~72 kDa

Storage & Solubility Information

Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.