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Anti-ARNT Antibody (6E603)

Catalog No. TMAB-02834 Copy Product Info
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Anti-ARNT Antibody (6E603) is a Mouse antibody targeting ARNT. Anti-ARNT Antibody (6E603) can be used in WB.

Anti-ARNT Antibody (6E603)

Copy Product Info
🥰Excellent
Catalog No. TMAB-02834

Anti-ARNT Antibody (6E603) is a Mouse antibody targeting ARNT. Anti-ARNT Antibody (6E603) can be used in WB.

Anti-ARNT Antibody
(6E603)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ARNT Antibody (6E603) is a Mouse antibody targeting ARNT. Anti-ARNT Antibody (6E603) can be used in WB.
Ig Type
IgG1, Kappa
Clone
6E603
Reactivity
Human (predicted:Rat)
Verified Activity
Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition: room temperature 2 h
Secondary ab: Goat Anti-Mouse IgG H&L (HRP)
Lysate: MCF-7, 293, HepG2, BRL
Protein loading quantity: 20 μg
Exposure time: 30 s
Predicted MW: 87 kDa
Observed MW: 100 kDa
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Antigen Details
Gene Name
ARNT
Gene ID
Protein Name
Aryl hydrocarbon receptor nuclear translocator
Function
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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