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Anti-DKK1 Antibody (2Q818)

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Catalog No. TMAB-05176 Copy Product Info
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Anti-DKK1 Antibody (2Q818) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (2Q818) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Anti-DKK1 Antibody
(2Q818)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DKK1 Antibody (2Q818) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (2Q818) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
Clone
2Q818
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityPlacenta.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAntagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Antigen Details
Immunogen
A synthesized peptide: human DKK1
Antigen Species
Human
Gene Name
DKK1
Gene ID
Protein Name
Dickkopf-related protein 1
Uniprot ID
Function
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Chemical Properties
Molecular WeightTheoretical: 29 kDa. Actual: 30-45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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