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Intetumumab (Synonyms: CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant Antibody)
Catalog No. T76812 Copy Product Info
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Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model.
Intetumumab
Copy Product Info🥰Excellent
Catalog No. T76812
Synonyms CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant Antibody
Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model.
Intetumumab
Cas No. 725735-28-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $263 | In Stock | In Stock | |
| 5 mg | $795 | In Stock | In Stock | |
| 10 mg | $1,350 | - | In Stock | |
| 25 mg | $1,960 | - | In Stock | |
| 50 mg | $2,680 | - | In Stock | |
| 100 mg | $3,650 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model. |
| In vitro | Intetumumab was able to inhibit integrin-mediated attachment of USPC-ARK-3 cells to the hyaluronan matrix and inhibit serum-induced migration of USPC cells at concentrations ranging from 0 to 5 μg/mL and treatment for 20 minutes. [1] |
| In vivo | Intetumumab administered intraperitoneally at a dose of 10 mg/kg to male nude mice was able to reduce the growth of A549 tumors and inhibit their spontaneous lung metastasis, as well as to reduce the number of mice presenting with lung metastases and the number of metastatic lesions per lung. [2] |
| Synonyms | CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant Antibody |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Integrin aV/ITGAV/CD51 |
| Molecular Weight | 145.56 kDa |
| Cas No. | 725735-28-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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