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Intetumumab
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Catalog No. T76812Cas No. 725735-28-4
Alias CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant Antibody
Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model.
Intetumumab
Intetumumab
😃Good
Catalog No. T76812Alias CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant AntibodyCas No. 725735-28-4
Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $263 | In Stock | In Stock | |
| 5 mg | $795 | In Stock | In Stock | |
| 10 mg | $1,350 | - | In Stock | |
| 25 mg | $1,960 | - | In Stock | |
| 50 mg | $2,680 | - | In Stock | |
| 100 mg | $3,650 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC)
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| Description | Intetumumab (CNTO 95) is a fully human anti-α(v)-integrin monoclonal antibody that is a radiosensitizer in xenograft tumor-bearing mice, inhibits tumor growth, and reduces lung metastases in the A549 NSCLC xenograft model. |
| In vitro | Intetumumab was able to inhibit integrin-mediated attachment of USPC-ARK-3 cells to the hyaluronan matrix and inhibit serum-induced migration of USPC cells at concentrations ranging from 0 to 5 μg/mL and treatment for 20 minutes. [1] |
| In vivo | Intetumumab administered intraperitoneally at a dose of 10 mg/kg to male nude mice was able to reduce the growth of A549 tumors and inhibit their spontaneous lung metastasis, as well as to reduce the number of mice presenting with lung metastases and the number of metastatic lesions per lung. [2] |
| Synonyms | CNTO95, CNTO095, CNTO 95, CNTO 095, Anti-Human CD51 Recombinant Antibody |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Integrin aV/ITGAV/CD51 |
| Molecular Weight | 145.56 kDa |
| Cas No. | 725735-28-4 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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