NPR1 Protein, Human, Recombinant (hFc)

Name: NPR1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-01985
Rating: 4.5 (1 reviews)

(Synonyms: NPR-A, GC-A, ANPR-A, ANPRA, ANP-A) Copy Product Info

Synonyms: NPR-A, GC-A, ANPR-A, ANPRA, ANP-A

Catalog No. TMPK-01985 Copy Product Info

NPR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is NP_000897.3.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$123	7-10 days	7-10 days
20 µg	$193	7-10 days	7-10 days
50 µg	$348	7-10 days	7-10 days
100 µg	$553	7-10 days	7-10 days
200 µg	$878	7-10 days	7-10 days
500 µg	$1,630	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Immobilized Human NPR1, hFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-NPR1 Antibody, hFc Tag with the EC50 of 13.9 ng/ml determined by ELISA (QC Test).
Description	NPR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is NP_000897.3.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc (IgG1)
Accession Number	NP_000897.3
Construction	Gly33-Glu473
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Synonyms	NPR-A, GC-A, ANPR-A, ANPRA, ANP-A
Research Background	NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.

Chemical Properties

Molecular Weight

74.84 kDa (Predicted); 90-120 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.