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Anti-MYB Antibody (7C786) (Alias: v myb avian myeloblastosis viral oncogene homolog, Transcriptional activat...)

Catalog No. TMAC-03474 Copy Product Info
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Anti-MYB Antibody (7C786) is a Rabbit antibody targeting MYB. Anti-MYB Antibody (7C786) can be used in FCM,ICC/IF,IHC,WB.

Anti-MYB Antibody (7C786)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03474
Alias v myb avian myeloblastosis viral oncogene homolog, Transcriptional activator Myb, Proto oncogene c Myb, Oncogene MYB, ONCOGENE AMV, MYB proto-oncogene transcription factor, efg, c-myb8B_CDS, c-myb14A_CDS, c-myb13A_CDS, c-myb10A_CDS, c-myb_CDS, Cmyb, C myb

Anti-MYB Antibody (7C786) is a Rabbit antibody targeting MYB. Anti-MYB Antibody (7C786) can be used in FCM,ICC/IF,IHC,WB.

Anti-MYB Antibody
(7C786)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MYB Antibody (7C786) is a Rabbit antibody targeting MYB. Anti-MYB Antibody (7C786) can be used in FCM,ICC/IF,IHC,WB.
Synonymsv myb avian myeloblastosis viral oncogene homolog, Transcriptional activator Myb, Proto oncogene c Myb, Oncogene MYB, ONCOGENE AMV, MYB proto-oncogene transcription factor, efg, c-myb8B_CDS, c-myb14A_CDS, c-myb13A_CDS, c-myb10A_CDS, c-myb_CDS, Cmyb, C myb
Ig Type
IgG
Clone
7C786
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human uterine neck tissue using anti-P-V-Myb+C-Myb (S11) antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-P-V-Myb+C-Myb (S11) antibody. Counter stained with hematoxylin.
3. ICC staining P-V-Myb+C-Myb (S11) in Ags cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of MCF-7 cells with P-V-Myb+C-Myb (S11) antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Myb family of transcription factors regulates proliferation, differentiation and apoptosis of hematopoletic cells. The avian myeloblastosis viral (v-Myb) protein is nuclear and binds to specific DNA sequences. The gene encoding for v-Myb is oncogenic, causing monoblastic leukemia and transforming myelomonocytic cells by deregulating the expression of specific target genes. v-Myb functions as a transcriptional activator, and it can repress biologically relevant genes such as Ets-2, which promotes macrophage differentiation. The proto-oncogene c-Myb encodes for a nuclear protein that plays a role in transcriptional regulation and may be essential for hematopoietic cell proliferation. A-Myb is also member of the Myb family that is expressed in proliferating B cell centroblasts. Transgenic mice overexpressing A-Myb posses enhanced hyperplasia of the lymph nodes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human V-Myb+C-Myb around the phosphorylation site of Ser11
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 72/75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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