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Anti-HGFR/c-Met Antibody (4N790) (Synonyms: RCCP2, MET proto-oncogene, receptor tyrosine kinase, HGFR, DFNB97...)

Catalog No. TMAC-02570 Copy Product Info
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Anti-HGFR/c-Met Antibody (4N790) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4N790) can be used in FCM,ICC/IF,IHC,WB.

Anti-HGFR/c-Met Antibody (4N790)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02570
Synonyms RCCP2, MET proto-oncogene, receptor tyrosine kinase, HGFR, DFNB97, c-Met, AUTS9

Anti-HGFR/c-Met Antibody (4N790) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4N790) can be used in FCM,ICC/IF,IHC,WB.

Anti-HGFR/c-Met Antibody
(4N790)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HGFR/c-Met Antibody (4N790) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4N790) can be used in FCM,ICC/IF,IHC,WB.
SynonymsRCCP2, MET proto-oncogene, receptor tyrosine kinase, HGFR, DFNB97, c-Met, AUTS9
Ig Type
IgG
Clone
4N790
Reactivity
Human
Verified Activity
1. Western blot analysis of Met on different lysates using anti-Met antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Met antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Met antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Met antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Met antibody. Counter stained with hematoxylin.
6. ICC staining Met in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. Flow cytometric analysis of Hela cells with Met antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a transmembrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibit transforming activity. Tyrosine phosphorylation of apparently normal Met protein has also been observed in certain human gastric carcinoma cell lines . The c-Met gene product has been identified as the cell-surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 155 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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