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Anti-CDK5 Antibody (8M152) (Synonyms: PSSALRE, cyclin-dependent kinase 5)

Catalog No. TMAC-00796 Copy Product Info
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Anti-CDK5 Antibody (8M152) is a Rabbit antibody targeting CDK5. Anti-CDK5 Antibody (8M152) can be used in FCM,IHC,IP,WB.

Anti-CDK5 Antibody (8M152)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00796
Synonyms PSSALRE, cyclin-dependent kinase 5

Anti-CDK5 Antibody (8M152) is a Rabbit antibody targeting CDK5. Anti-CDK5 Antibody (8M152) can be used in FCM,IHC,IP,WB.

Anti-CDK5 Antibody
(8M152)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CDK5 Antibody (8M152) is a Rabbit antibody targeting CDK5. Anti-CDK5 Antibody (8M152) can be used in FCM,IHC,IP,WB.
SynonymsPSSALRE, cyclin-dependent kinase 5
Ig Type
IgG
Clone
8M152
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Cdk5 on Hela cell lysates using anti-Cdk5 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Cdk5 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Cdk5 antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Hela cells with Cdk5 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1?C3, PITALRE and PITSLRE. Cdk5 is thought to be involved in the G1-S transition of the cell cycle and is highly expressed in mature neurons. Activity of Cdk5 increases significantly during neuronal differentiation. Cdk5 has been postulated to be a neurofilament or tau protein kinase, based on its ability to phosphorylate these proteins in vitro.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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