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Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900)

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Catalog No. TMAB-02218

Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) is a Rabbit antibody targeting Acetyl-Histone H3.1 (Lys24). Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) can be used in WB,ICC/IF,IP,ChIP.

Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900)

Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900)

😃Good
Catalog No. TMAB-02218
Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) is a Rabbit antibody targeting Acetyl-Histone H3.1 (Lys24). Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) can be used in WB,ICC/IF,IP,ChIP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) is a Rabbit antibody targeting Acetyl-Histone H3.1 (Lys24). Anti-Acetyl-Histone H3.1 (Lys24) Antibody (5N900) can be used in WB,ICC/IF,IP,ChIP.
Ig Type
IgG
Clone
5N900
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:50-200; IP: 1:20-50; ChIP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC).
Tissue SpecificityExpressed in testicular cells.Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Antigen Details
Immunogen
A synthesized peptide: human Histone H3.1 around the acetylation site of K24
Antigen Species
Human
Gene Name
H3C1
Gene ID
Protein Name
Histone H3.1
Uniprot ID
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H3 is deposited into chromatin exclusively through a DNA replication-coupled pathway that can be associated with either DNA duplication or DNA repair synthesis during meiotic homologous recombination.
Chemical Properties
Molecular WeightTheoretical: 15 kDa. Actual: 15 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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